Spruce resin is a mixture of hundreds of compounds produced by a coniferous tree. The purpose of the resin is to protect the tree from external influences including different microbes (bacteria, fungi, yeast, mold) and insects, as well as dehydration and other physical stress. The tree produces at first so called physiological resin providing physical barrier and later other components that are highly critical for the long term protection and healing of the defect. The resin composition is based on a natural evolution throughout millions of years enabling the trees to live in a hostile environment.

To capture this nature’s unique defence mechanism into use as medical devices in the modern medicine requires evidence on safety, efficacy and product functionality according to ISO 13485 requirements.

Repolar uses unique and patented processes in manufacturing of solutions including the active components of the natural Spruce resin. The processes are designed to provide stable and safe solutions maintaining the broad natural effectiveness of the resin that protects and heals the coniferous trees.

With extensive studies the resin based products produced by Repolar Pharmaceuticals have shown to be safe. Only known contraindication is resin allergy caused by components that are known to cause allergic reactions in people who are sensitive to natural resin.

Resin is collected from trees in Northern Finland without harming them in this process. Controlled collection and quality control ensures the quality of the resin with full natural efficacy.

Repolar Pharmaceuticals Oy has made extensive research on the resin compounds and their efficacy, functionality and safety. The Doctoral Thesis of Arno Sipponen (2013) provides comprehensive overview of the results.

The extensive research done by Repolar on its resin components extracted with novel technique has shown them to be.